CDOS

HDL, DIRECT

Mnemonic: HDLD

CPT Code: 83718

Test Link (Copy)

Charge Code

70111337

Specimen Type

PLASMA/SERUM

Specimen Container

GREEN, YELLOW, RED

Specimen Handling

SEPARATE FROM CELLS WITHIN 2 HOURS. KEEP CAPPED AND VERTICAL.

Temperature

REFRIGERATED

Methodology

CHEMICAL METHOD. FREE CHOLESTEROL IN NON-HDL-LIPOPROTEINS IS SOLUBILIZED AND CONSUMED BY CHOLESTEROL OXIDASE, PEROXIDASE, AND DSBMT TO GENERATE A COLORLESS END PRODUCT. THEN A UNIQUE DETERGENT SELECTIVELY SOLUBILIZES HDL. HDL CHOLESTEROL REACTS WITH CHOLESTEROL ESTERASE AND CHOLESTEROL OXIDASE, CHROMOGENS, TO PRODUCE A COLOR PRODUCT.

Volume

0.5 ML

Minimum Volume

0.3 ML

Additional Information

MANY EPIDEMIOLOGICAL INVESTIGATIONS HAVE DEMONSTRATED THE STRONG AND INDEPENDENT INVERSE ASSOCIATION BETWEEN HDL-CHOLESTEROL AND THE RISK OF CORONARY ARTERY DISEASE. IT HAS BEEN PROPOSED THAT HDL PARTICLES, THROUGH THE UPTAKE AND TRANSPORT OF CHOLESTEROL FROM PERIPHERAL TISSUE TO THE LIVER (REVERSE CHOLESTEROL TRANSPORT), PROTECTS AGAINST THE DEVELOPMENT OF ATHEROMATOUS PLAQUES.

Stability

7 DAYS, 8 HOURS ROOM TEMPERATURE OR FREEZE

Reference Range Information

AMERICAN HEART ASSOCIATION RECOMMENDS: HDL >60 DESIRABLE, 40-59 BORDERLINE HIGH, <40 HIGH. INACCURATE RESULTS (USUALLY NEGATIVE INTERFERENCE) MAY BE PRODUCED IN PATIENT SAMPLES WITH ELEVATED SERUM IMMUNOGLOBULIN LEVELS. IN VERY RARE CASES GAMMOPATHY, ESPECIALLY MONOCLONAL IGM (WALDENSTRÖM’S MACROGLOBULINEMIA), MAY CAUSE UNRELIABLE RESULTS. FALSELY LOW RESULTS MAY BE OBTAINED IN PATIENTS WITH TYPE III HYPERLIPIDEMIA

Turn Around Time

NEXT DAY

Place of Service

GRITMAN MEDICAL CENTER

Result Code	Result Name	Sex	Units of Measure
HDLD	HDL-DIRECT	MALE	MG/DL
HDLD	HDL-DIRECT	FEMALE	MG/DL

Reflex Order Code	Reflex Order Name	Reflex CPT4

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