T-Cell Receptor Gene Rearrangements Profile, gamma and beta
Test Code: 481080
Performing Lab: LabCorp
CPT Code: 81342 001 81340 001
Synonym
TCRB Gene Clonality Assay; TCRG Gene Clonality Assay
Specimen Type
Whole blood, bone marrow, formalin-fixed, paraffin-embedded (FFPE) tissue block or slides, fresh or frozen tissue
Specimen Container
Lavender-top (EDTA) tube, yellow-top (ACD) tube, green-top (heparin) tube, Tan-top (K2-EDTA) tube, and Pink-top (K2-EDTA) tube, FFPE tissue block or slides, tissue in RPMI or frozen
Volume
3 to 5 mL whole blood, 1 mL bone marrow, five unstained slides at 10 uM or formalin-fixed, paraffin-embedded tissue block, tissue in RPMI or frozen.
Minimum Volume
0.5 mL whole blood, 0.5 mL bone marrow, two unstained slides at 10uM
Specimen Handling
Fresh tissue should be placed in RPMI medium or shipped frozen on dry ice. Small samples (eg, punch biopsies, fine- needle aspirate) will also be accepted. To avoid delays in turnaround time when requesting multiple tests on frozen samples, PLEASE SUBMIT SEPARATE SPECIMENS FOR EACH TEST REQUESTED.
Unacceptable Conditions
Frozen whole blood/bone marrow; quantity not sufficient for analysis; tumor block containing no tumor tissue; broken or stained slides
Temperature
Maintain blood, bone marrow or tissue in RPMI at 2(degrees)C -8(degrees)C, FFPE specimens at room temperature, tissue at -80(degrees)C
Methodology
Polymerase chain reaction (PCR)
| Result Code | Result Name | LOINC |
|---|---|---|
| 480709 | T-Cell PCR Interpretation | 21753-9 |
| 480826 | T Clonal Size | UNLOINC |
| 481156 | Block Number: | UNLOINC |
| 489024 | Director Review: | 72486-4 |
| 480711 | Methodology: | 49549-9 |
| 481531 | References: | UNLOINC |
| 480986 | TCRB Gene Clonality Results: | 21751-3 |
| 480987 | Clonal Size: | UNLOINC |
| 480989 | Block Number: | UNLOINC |
| 480993 | Director Review: | 72486-4 |
| 480984 | Methodology: | 49549-9 |
| 480994 | References: | UNLOINC |
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