CDOS

Catecholamines, Fractionated, Plasma

Test Code: 084152

Performing Lab: LabCorp

CPT Code: 82384 001

Test Link (Copy)

Synonym

Adrenalin(R), Plasma; Dopamine, Plasma; Epinephrine, Plasma; Noradrenaline, Plasma; Norepinephrine, Plasma; Plasma Catecholamines

Specimen Type

Plasma, FROZEN

Specimen Container

Lavender-top (EDTA) tube or green-top (heparin) tube

Volume

1.5 mL (plasma)

Minimum Volume

0.7 mL (plasma, NOTE:This volume does not allow for repeat testing).

Specimen Handling

Draw blood in CHILLED lavender-top (EDTA) tube. Invert to mix with preservatives. Centrifuge and transfer the plasma to a labeled plastic transfer tube. Place on ice immediately (do NOT refrigerate) and freeze separated plasma within 4 hours of collection. IMPORTANT: The patient should be in a fully recumbent position (lying down) for at least 20 minutes before and during sample collection. TO AVOID DELAYS IN TURNAROUND TIME WHEN REQUESTING MULTIPLE TESTS ON FROZEN SAMPLES, PLEASE SUBMIT SEPARATE FROZEN SPECIMENS FOR EACH TEST REQUESTED.

Patient Prep

Patient should not be smoking for four to six hours. Walnuts, bananas, and ?-methyldopa (Aldometr) should be avoided for a week prior to sampling. Other drug interference may occur, including epinephrine and epinephrine-like drugs (eg, nosedrops, sinus and cough preparations, bronchodilators, appetite suppressants). Test is unreliable in subjects on levodopa or methenamine mandelate. Avoid patient stress.2 See Limitations. An indwelling heparinized venous catheter is advocated, since venipuncture can cause an increase in the substances for which testing is being done. Patient should remain supine in quiet surroundings for at least 30 minutes.

Unacceptable Conditions

Specimen not drawn in correct tube; plasma not received frozen

Temperature

FREEZE. After centrifugation, the plasma must be frozen immediately.

Methodology

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Stability

Room Temperature: Unstable
Refrigerated: Unstable
Frozen: 14 days

Result Code	Result Name	LOINC
081471	Norepinephrine	2666-6
081489	Epinephrine	2230-1
081497	Dopamine	2216-0

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