CDOS

NMR LipoProfile(R) With Lipids (Without Graph)

Test Code: 884247

Performing Lab: LabCorp

CPT Code: 80061 001 83704 001

Test Link (Copy)

Synonym

Cholesterol; Lipoprotein Analysis (LDL-P, HDL-P, LDL Size), Expanded

Specimen Type

Spun NMR LipoTube (preferred), serum from a plain red-top tube, plasma from a lavender-top (EDTA-no gel), OR green-top (heparin-no gel) tube. Keep refrigerated and SHIP WITH FROZEN COOL PACKS.

Specimen Container

NMR LipoTube (black-and-yellow-top tube) is the preferred container, plain red-top tube, lavender-top (EDTA-no gel) tube, OR green-top (heparin-no gel) tube.

Volume

2 mL

Minimum Volume

1 mL

Specimen Handling

Collect specimen in NMR LipoTube (black-and-yellow-top tube), which is the preferred container. Plain red-top, green-top (heparin-no gel), or lavender-top (EDTA-no gel) tubes are also acceptable. Serum or plasma drawn in gel-barrier collection tubes other than the NMR LipoTube should NOT be used. THE LIPOTUBE IS THE ONLY ACCEPTABLE GEL-BARRIER TUBE. Gently invert tube 8 to 10 times to mix contents and allow specimen to clot for 30 minutes upright at room temperature prior to centrifugation (Plasma tubes should not clot). Centrifuge specimen within two hours of collection at 1600 to 1800 xg for 10 to 15 minutes to separate serum/plasma from the red cells and to avoid red cell contamination during shipment. If the sample cannot be centrifuged immediately, the sample should be refrigerated (at 2 degrees Celsius to 8 degrees Celsius) and centrifuged within 24 hours of collection. NOTE: Centrifuging the specimen while still cold may negatively affect the migration of the gel to the serum/red cell interface and may increase the likelihood of specimens being contaminated with red cells during shipment. All specimens should be centrifuged by the client, PRIOR to shipment to LabCorp, to ensure sample integrity. Do NOT open NMR LipoTube (black- and-yellow-top). Immediately after centrifugation, pipette separated red-top serum or green-top/lavender-top plasma into a transport tube and label accordingly (serum, heparin plasma, EDTA plasma). Keep samples refrigerated until shipment to the laboratory, and SHIP WITH FROZEN COOL PACKS.

Patient Prep

Patient should be fasting for eight hours.

Unacceptable Conditions

Unspun specimens; plasma/serum contaminated with red cells; citrated plasma (light blue-top tube); gross hemolysis; specimen received in inappropriate container; specimen stored at room temperature for more than a total preanalytical time of 24 hours; specimen more than six days old.

Temperature

Refrigerate all acceptable tube types as soon as possible after centrifugation and within 24 hours of collection. Keep refrigerated prior to shipment, and SHIP ON FROZEN COOL PACKS. Do NOT store at room temperature. Do NOT freeze the sample. Sample is stable refrigerated for six days.

Methodology

Nuclear magnetic resonance (NMR) NOTE: The NMR method for Triglycerides, unlike the routine chemical method, is not affected by endogenous glycerol which might be found in very rare clinical conditions such as Hyperglycerolemia (glycerol kinase deficiency-GKD), an X-linked genetic disorder. Large quantitative differences in the chemical and NMR method results may be attributable to high blood glycerol.

TAT

2 - 3 days

Result Code	Result Name	LOINC
884294	LDL-P	54434-6
123479	LDL-C (NIH Calc)	13457-7
123475	HDL-C	2085-9
123476	Triglycerides	2571-8
123477	Cholesterol, Total	2093-3
884296	HDL-P (Total)	49748-7
884297	Small LDL-P	43727-7
884309	LDL Size	17782-4
884312	LP-IR Score	62255-5
884310	PDF	UNLOINC
123469	Historical Reporting	UNLOINC

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